Trading Arrangements, by Individual
Trading Arrangements, by Individual [Table]
Deferred Tax Asset [Domain]
Deferred Tax Asset [Domain]
Performance stock units issued and outstanding (unvested) under the 2020 Plan (in shares)
Common Stock, Capital Shares Reserved for Future Issuance, Effect Of Performance Stock Units Available For Future Grant
Common Stock, Capital Shares Reserved for Future Issuance, Effect Of Performance Stock Units Available For Future Grant
Remaining useful life (in years)
Intangible Asset, Finite-Lived, Remaining Amortization Period
Trading Arrangement:
Trading Arrangement [Axis]
Asset Acquisition [Table]
Asset Acquisition [Table]
Maximum
Maximum [Member]
Statistical Measurement [Domain]
Statistical Measurement [Domain]
Cash and Cash Equivalents
Cash and Cash Equivalents, Unrestricted Cash and Cash Equivalents, Policy [Policy Text Block]
Alkeus Pharmaceuticals, Inc.
Alkeus Pharmaceuticals, Inc. [Member]
Alkeus Pharmaceuticals, Inc.
Title of 12(b) Security
Title of 12(b) Security
Debt Securities, Available-for-Sale [Table]
Debt Securities, Available-for-Sale [Table]
Document Fiscal Year Focus
Document Fiscal Year Focus
Seller transaction costs paid by the Company
Business Combination, Acquisition-Related Cost, Expense
Irvine, California
Irvine, California [Member]
Irvine, California
Adjustment to Compensation, Amount
Adjustment to Compensation Amount
Agent fee (as a percent)
Sale of Stock, Sales Agent Fee, Percentage Of Gross Proceeds
Sale of Stock, Sales Agent Fee, Percentage Of Gross Proceeds
Financial Instrument [Axis]
Financial Instrument [Axis]
Number of Shares
Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Customer [Axis]
Customer [Axis]
Segment Reporting [Abstract]
Schedule of Expected Future Amortization Expense
Intangible Asset, Finite-Lived, and Capitalized Cost, Software to be Sold, Leased, or Marketed, Estimated Amortization Expense [Table Text Block]
Common stock, $0.0001 par value; 200,000,000 shares authorized; 49,303,413 shares issued and outstanding at September 30, 2026 (unaudited); 42,553,931 shares issued and outstanding at December 31, 2025
Common Stock, Value, Issued
2027
Lessee, Operating Lease, Liability, to be Paid, Year One
Schedule of Restricted Stock Unit Activity
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Accrued payroll and benefits
Employee-related Liabilities, Current
Development and Regulatory Milestone
Development And Regulatory Milestone [Member]
Development And Regulatory Milestone
Service condition period for full vesting (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Requisite Service Period
Line of Credit
Line of Credit [Member]
Restatement Determination Date
Restatement Determination Date
Pre-funded warrants to purchase common stock (in shares)
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Amendment Flag
Amendment Flag
Current liabilities:
Liabilities, Current [Abstract]
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Inventory, non-current
Inventory, non-current
Inventory, Noncurrent
Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Property and equipment, net
Business Combination, Recognized Asset Acquired, Property, Plant, and Equipment
(Less): Tenant improvement allowance
Lessee, Operating Lease, Liability, Tenant Improvement Allowance
Lessee, Operating Lease, Liability, Tenant Improvement Allowance
Option Holder Settlement
Option Holder Settlement [Member]
Option Holder Settlement
Common stock issued, gross (in shares)
Business Combination, Consideration Transferred, Equity Interest, Share Issued, Number of Shares, Gross
Business Combination, Consideration Transferred, Equity Interest, Share Issued, Number of Shares, Gross
Business Combination, Deferred Consideration, Type [Domain]
Business Combination, Deferred Consideration, Type [Domain]
Business Combination, Deferred Consideration, Type [Domain]
Number of employment arrangements with executive officers
Number Of Employment Arrangements With Executive Officers
Number Of Employment Arrangements With Executive Officers
Common stock issued
Fair value of common stock issued in connection to acquisitions
Stock Issued During Period, Value, Acquisitions
RELATED PARTY TRANSACTIONS
Related Party Transactions Disclosure [Text Block]
Adjustment to Non-PEO NEO Compensation Footnote
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
Pharmakon Credit Facility, Tranche Two
Pharmakon Credit Facility, Tranche Two [Member]
Pharmakon Credit Facility, Tranche Two
Entity Address, State or Province
Entity Address, State or Province
Preferred stock purchased
Payments to Acquire Equity Securities, FV-NI
Granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
PEO Total Compensation Amount
PEO Total Compensation Amount
Aggregate consideration paid
Payments For Asset Acquisitions
Payments For Asset Acquisitions
Common stock, par value (usd per share)
Common Stock, Par or Stated Value Per Share
Asset Acquisition [Axis]
Asset Acquisition [Axis]
Cash equivalents:
Cash and Cash Equivalents [Abstract]
Intangible assets, net
Intangible assets, net
Intangible Asset, Excluding Goodwill, after Accumulated Amortization
Outstanding, beginning balance (in shares)
Outstanding, ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Three Customers
Three Customers [Member]
Three Customers
Weighted-average shares outstanding, basic (in shares)
Weighted-average shares outstanding - basic (in shares)
Weighted Average Number of Shares Outstanding, Basic
Raw materials
Inventory, Raw Materials, Noncurrent, Net of Reserves
Inventory, Raw Materials, Noncurrent, Net of Reserves
Net amortization/accretion of marketable securities
Accretion (Amortization) of Discounts and Premiums, Investments
Long-term investments
Long-Term Investments
Outstanding Aggregate Erroneous Compensation Amount
Outstanding Aggregate Erroneous Compensation Amount
Fair Value, by Balance Sheet Grouping [Table]
Fair Value, by Balance Sheet Grouping [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Number of reportable segments
Number of Reportable Segments
Total current liabilities
Liabilities, Current
Contingent consideration value allocable to partially vested option holders
Business Combination, Contingent Consideration, Allocated To Partially Vested Option Holders, Percentage
Business Combination, Contingent Consideration, Allocated To Partially Vested Option Holders, Percentage
2030
Lessee, Operating Lease, Liability, to be Paid, Year Four
Work in progress
Inventory, Work in Process, Net of Reserves
Stock options issued and outstanding (unvested and vested) under the 2020 and 2016 Plans (in shares)
Common Stock, Capital Shares Reserved for Future Issuance, Effect Of Stock Options Issued And Outstanding
Common Stock, Capital Shares Reserved for Future Issuance, Effect Of Stock Options Issued And Outstanding
Entity Address, City or Town
Entity Address, City or Town
Total acquisition cost
Asset Acquisition, Consideration Transferred
Granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
iRenix Medical, Inc.
iRenix Medical, Inc. [Member]
iRenix Medical, Inc.
Statement of Financial Position [Abstract]
Annual increase in rent (as a percent)
Lessee, Operating Lease, Annual Rent Increase, Percent
Lessee, Operating Lease, Annual Rent Increase, Percent
Award Timing MNPI Disclosure
Award Timing MNPI Disclosure [Text Block]
Vested (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Product sales, net
Product sales, net
Product [Member]
Pharmakon Credit Facility
Pharmakon Credit Facility [Member]
Pharmakon Credit Facility
Royalty expense
Royalty Expense
Total future amortization
Intangible Asset, Finite-Lived, after Accumulated Amortization
Peer Group Total Shareholder Return Amount
Peer Group Total Shareholder Return Amount
Proceeds from sale of common stock under employee stock purchase plan
Proceeds from Stock Plans
Restricted stock units issued and outstanding (unvested) under the 2020 Plan (in shares)
Common Stock, Capital Shares Reserved for Future Issuance, Effect Of Restricted Stock Units Available For Future Grant
Common Stock, Capital Shares Reserved for Future Issuance, Effect Of Restricted Stock Units Available For Future Grant
(Less): Accumulated amortization
Intangible Asset, Finite-Lived, Accumulated Amortization
Level 2
Fair Value, Inputs, Level 2 [Member]
Other income (expense):
Nonoperating Income (Expense) [Abstract]
Total Shareholder Return Vs Peer Group
Total Shareholder Return Vs Peer Group [Text Block]
Tenant improvement allowance
Lessee, Tenant Improvement Allowance
Lessee, Tenant Improvement Allowance
Credit facility, aggregate principal amount
Line of Credit Facility, Maximum Borrowing Capacity
Other comprehensive income (loss)
Other Comprehensive Income (Loss), Net of Tax
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Revenue Benchmark
Revenue Benchmark [Member]
Maximum milestone payment amount
Asset Acquisition, Contingent Consideration, Range of Outcomes, Maximum, Amount
Asset Acquisition, Contingent Consideration, Range of Outcomes, Maximum, Amount
Thereafter
Lessee, Operating Lease, Liability, to be Paid, After Current Fiscal Year
Lessee, Operating Lease, Liability, to be Paid, After Current Fiscal Year
Issuance of common stock upon the vesting of restricted stock units (in shares)
Stock Issued During Period, Shares, Restricted Stock Award, Gross
Concentration Risk Type [Axis]
Concentration Risk Type [Axis]
Schedule of Long-term Debt Instruments [Table]
Schedule of Long-Term Debt Instruments [Table]
Recently Issued or Effective Accounting Standards
New Accounting Pronouncements, Policy [Policy Text Block]
Net Loss per Share
Earnings Per Share, Policy [Policy Text Block]
Other accrued liabilities
Business Combination, Recognized Liability Assumed, Other Liability, Current
Underwriter purchase option (in days)
Sale of Stock, Underwriter Purchase Option, Term
Sale of Stock, Underwriter Purchase Option, Term
Additions of property and equipment included within accounts payable and other accrued liabilities
Capital Expenditures Incurred but Not yet Paid
Grandpharma
Grandpharma [Member]
Grandpharma
Loss on disposal of property and equipment
Gain (Loss) on Disposition of Property Plant Equipment
Cash Settled Accelerated Options
Cash Settled Accelerated Options [Member]
Cash Settled Accelerated Options
Amortization of debt issuance costs
Amortization of Debt Issuance Costs
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
MERGERS AND ACQUISITIONS
Asset Acquisition [Text Block]
Accrued milestone achievement
Accrued Milestone Achievement, Current
Accrued Milestone Achievement, Current
Related Party [Axis]
Related and Nonrelated Parties [Axis]
Schedule of Reconciliation of the Contingent Consideration Liability
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Research and Development Costs
Research and Development Expense, Policy [Policy Text Block]
Acquisition-date fair value, gross
Business Combination, Recognized Asset Acquired, Identifiable Intangible Asset, Excluding Goodwill
Long-term debt, net
Long-Term Debt
Exercise price per warrant (usd per share)
Class of Warrant or Right, Exercise Price of Warrants or Rights
Schedule of Future Contractual Lease Payments
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Document Period End Date
Document Period End Date
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Regulatory Approval Milestone
Regulatory Approval Milestone [Member]
Regulatory Approval Milestone
Net cash used in investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Equity Awards Adjustments, Excluding Value Reported in Compensation Table
Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member]
Unrecognized tax benefits
Unrecognized Tax Benefits
Preferred stock, outstanding (in shares)
Preferred Stock, Shares Outstanding
2028
Lessee, Operating Lease, Liability, to be Paid, Year Two
Earnings Per Share, Basic [Abstract]
Earnings Per Share, Basic [Abstract]
Security Exchange Name
Security Exchange Name
Purchase Agreement
Purchase Agreement [Member]
Purchase Agreement
Effective interest rate (as a percent)
Debt Instrument, Interest Rate, Effective Percentage
Accounting Standards Codification 480
Accounting Standards Codification 480 [Member]
Accounting Standards Codification 480
Business Combination, Accounting Codification [Domain]
Business Combination, Accounting Codification [Domain]
Business Combination, Accounting Codification [Domain]
Granted (usd per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Lessee, Lease, Description [Line Items]
Lessee, Lease, Description [Line Items]
Total liabilities measured at fair value
Liabilities, Fair Value Disclosure
Accumulated other comprehensive income (loss)
Accumulated Other Comprehensive Income (Loss), Net of Tax
Entity Shell Company
Entity Shell Company
Change in fair value
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings
Operating lease liability, current
Operating Lease, Liability, Current
Schedule of Property and Equipment, Net
Property, Plant, and Equipment [Table Text Block]
NET LOSS PER SHARE
Earnings Per Share [Text Block]
Name
Outstanding Recovery, Individual Name
Earnings Per Share [Abstract]
Earnings Per Share [Abstract]
Proceeds from maturities of marketable securities
Proceeds from Sale and Maturity of Marketable Securities
Award Timing, How MNPI Considered
Award Timing, How MNPI Considered [Text Block]
Document Fiscal Period Focus
Document Fiscal Period Focus
Peer Group Issuers, Footnote
Peer Group Issuers, Footnote [Text Block]
Total liabilities
Liabilities
Trading Symbol
Trading Symbol
Discount rate
Measurement Input, Discount Rate [Member]
Geographical [Domain]
Geographical [Domain]
Schedule of Interest Expense
Interest Income and Interest Expense Disclosure [Table Text Block]
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member]
Non-cash lease expense
Operating Lease, Noncash Expense
Operating Lease, Noncash Expense
Pension Adjustments Prior Service Cost
Pension Adjustments Prior Service Cost [Member]
Unrecognized compensation expense
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Schedule of Fair Value of the Assets Acquired and Liabilities Assumed
Business Combination, Recognized Asset Acquired and Liability Assumed [Table Text Block]
Company Selected Measure Name
Company Selected Measure Name
Sale of Stock [Domain]
Sale of Stock [Domain]
Purchases of marketable securities
Payments to Acquire Debt Securities, Available-for-Sale
Income Tax Disclosure [Abstract]
Debt securities, available for sale and cash and cash equivalents
Debt Securities, Available-For-Sale And Cash And Cash Equivalents, Fair Value Disclosure
Debt Securities, Available-For-Sale And Cash And Cash Equivalents, Fair Value Disclosure
Amortization of debt-related costs
Amortization of Debt Issuance Costs and Discounts
Business Combination, Contingent Consideration, Type [Axis]
Business Combination, Contingent Consideration, Type [Axis]
Anterior In-License Agreement
Anterior In-License Agreement [Member]
Anterior In-License Agreement
Unrealized gain (loss) on marketable securities and cash equivalents
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
Supplemental Disclosures From Noncash, Investing and Financing Activities:
Noncash Investing and Financing Items [Abstract]
Accounting Standards Codification 718
Accounting Standards Codification 718 [Member]
Accounting Standards Codification 718
Long-term debt, gross
Long-Term Debt, Gross
Restricted stock units — unvested
Share-Based Payment Arrangement, Equity Instruments Other Than Options, Restricted Stock Units, Unvested [Member]
Share-Based Payment Arrangement, Equity Instruments Other Than Options, Restricted Stock Units, Unvested
Amortized cost
Equity Securities, FV-NI, Cost
Other accrued liabilities
Increase (Decrease) in Other Accrued Liabilities
Rent abatement
Incentive from Lessor
Related Party Transactions [Abstract]
Cash Flows From Operating Activities:
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Other receivables
Other Receivables, Net, Current
Compensation Amount
Outstanding Recovery Compensation Amount
Individual:
Individual [Axis]
Weighted-average shares outstanding - diluted (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Bobak Azamian
Bobak Azamian [Member]
Bobak Azamian
Retention bonuses payable
Business Combination, Contingent Consideration, Retention Bonuses, Payable
Business Combination, Contingent Consideration, Retention Bonuses, Payable
Authorized consideration
Sale of Stock, Consideration Amount Authorized
Sale of Stock, Consideration Amount Authorized
Entity Emerging Growth Company
Entity Emerging Growth Company
Equity Valuation Assumption Difference, Footnote
Equity Valuation Assumption Difference, Footnote [Text Block]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Useful lives of assets (in years)
Property, Plant, and Equipment, Useful Life
Net assets acquired
Business Combination, Recognized Asset Acquired to Liability Assumed, Excess (Less)
Underlying Security Market Price Change
Underlying Security Market Price Change, Percent
Draw on credit facility
Proceeds from Lines of Credit
Commercial paper
Commercial Paper [Member]
U.S. Treasury securities
US Treasury Securities [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
(Less): Imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Other non-current assets
Increase (Decrease) in Other Noncurrent Assets
Restricted Cash
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Cash paid for our current lease
Operating Lease, Payments
Award Timing Predetermined
Award Timing Predetermined [Flag]
Restricted cash
Restricted Cash, Current
Debt Securities, Available-for-Sale [Line Items]
Debt Securities, Available-for-Sale [Line Items]
Adjustment To PEO Compensation, Footnote
Adjustment To PEO Compensation, Footnote [Text Block]
Recognition of stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Level 1
Fair Value, Inputs, Level 1 [Member]
Consideration Type [Axis]
Business Combination, Consideration Type [Axis]
Business Combination, Consideration Type
State
State and Local Income Tax Expense (Benefit), Continuing Operations
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Payment for landlord in base rent over the remaining lease term
Total future lease payments, undiscounted
Lessee, Operating Lease, Liability, to be Paid
Square feet of office space
Area of Real Estate Property
Unvested
Share-Based Compensation Arrangement By Share-based Payment Award, Options, Nonvested, Aggregate Intrinsic Value
Share-Based Compensation Arrangement By Share-based Payment Award, Options, Nonvested, Aggregate Intrinsic Value
Marketable securities:
Debt Securities, Available-for-Sale [Abstract]
Number of leases
Lessee, Operating Lease, Number Of Lease Contracts
Lessee, Operating Lease, Number Of Lease Contracts
Outstanding, beginning balance (usd per share)
Outstanding, ending balance (usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Warrant issue price (usd per share)
Class of Warrant or Right, Price Per Share
Class of Warrant or Right, Price Per Share
Intangible Assets, Net
Goodwill and Intangible Assets, Intangible Assets, Policy [Policy Text Block]
All Executive Categories
All Executive Categories [Member]
Elanco
Elanco [Member]
Elanco
Government-related debt securities
US Government Debt Securities [Member]
Pension Adjustments Service Cost
Pension Adjustments Service Cost [Member]
Preferred stock, par value (usd per share)
Preferred Stock, Par or Stated Value Per Share
Pre-funded warrants reserved for future issuance (in shares)
Class of Warrant Or Right, Reserved for Future Issuance
Class of Warrant Or Right, Reserved for Future Issuance
Depreciation
Depreciation
Plan Name [Domain]
Plan Name [Domain]
Asset Acquisition [Domain]
Asset Acquisition [Domain]
Antidilutive Securities [Axis]
Antidilutive Securities [Axis]
Beginning balance (usd per share)
Ending balance (usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Selling and marketing
Selling and Marketing Expense
Operating lease right-of-use assets
Operating Lease, Right-of-Use Asset
Concentration Risk Type [Domain]
Concentration Risk Type [Domain]
Upon Execution of the Novation Agreement
Upon Execution of the Novation Agreement [Member]
Upon Execution of the Novation Agreement
Schedule of Computation of Basic and Diluted Net Loss Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Fair Value Disclosures [Abstract]
Accumulated amortization of debt issuance costs
Accumulated Amortization, Debt Issuance Costs
Debt Disclosure [Abstract]
Debt Instrument, Name [Domain]
Debt Instrument, Name [Domain]
Royalty
Royalty [Member]
SEGMENT REPORTING
Segment Reporting [Text Block]
Minimum
Minimum [Member]
Expiration Date
Trading Arrangement Expiration Date
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Liabilities:
Liabilities [Abstract]
Schedule of Intangible Assets, Net
Intangible Asset, Finite-Lived, Amortization Expense [Table Text Block]
Income Statement Location [Axis]
Location, Statement of Income, Balance [Axis]
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Cash and cash equivalents
Money market funds
Total cash equivalents
Cash and Cash Equivalents, Fair Value Disclosure
Outstanding (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member]
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Number of securities with contractual maturity between one and three years
Debt Securities, Available-for-Sale, Contractual Maturities Greater Than Twelve Months, Number of Securities
Debt Securities, Available-for-Sale, Contractual Maturities Greater Than Twelve Months, Number of Securities
Business Combination [Line Items]
Business Combination [Line Items]
Exercisable (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Aggregate Pension Adjustments Service Cost
Aggregate Pension Adjustments Service Cost [Member]
Laboratory equipment
Other Machinery and Equipment [Member]
Proceeds from issuance of common stock, net of paid issuance costs
Proceeds from Issuance of Common Stock
Sales-based Milestones
Sales-Based Milestones [Member]
Sales-based Milestones
Common stock, authorized (in shares)
Common Stock, Shares Authorized
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Initial useful life (in years)
Intangible Asset, Finite-Lived, Useful Life
Deferred Tax Asset, Valuation Allowance [Table]
Deferred Tax Asset, Valuation Allowance [Table]
Stock issued (in shares)
Sale of Stock, Number of Shares Issued in Transaction
Exercise Price
Award Exercise Price
Cash Flows From Investing Activities:
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Weighted-average remaining lease term (years)
Lessee, Operating Lease, Remaining Lease Term
Related Party Transaction [Axis]
Related Party Transaction [Axis]
Segment Reporting [Line Items]
Segment Reporting [Line Items]
Document Quarterly Report
Document Quarterly Report
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member]
Segments [Domain]
Segments [Domain]
2023 Shelf Registration Statement
2023 Shelf Registration Statement [Member]
2023 Shelf Registration Statement
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
2016 Plan
Equity Incentive Plan 2016 [Member]
Equity Incentive Plan 2016
Property and Equipment, Net
Property, Plant, and Equipment [Policy Text Block]
CREDIT FACILITY AGREEMENT
Debt Disclosure [Text Block]
Eligible milestone payment amount
Asset Acquisition, Consideration Transferred, Contingent Consideration, Milestone Payment
Asset Acquisition, Consideration Transferred, Contingent Consideration, Milestone Payment
Awards Close in Time to MNPI Disclosures, Table
Awards Close in Time to MNPI Disclosures [Table Text Block]
Other receivables
Increase (Decrease) in Other Receivables
Deferred consideration
Business Combination, Consideration Transferred, Deferred
Business Combination, Consideration Transferred, Deferred
Business Combination [Table]
Business Combination [Table]
Equity Component [Domain]
Equity Component [Domain]
PEO Actually Paid Compensation Amount
PEO Actually Paid Compensation Amount
Measurement Input Type [Domain]
Measurement Input Type [Domain]
Business Combination, Asset Acquisition, Transaction between Entities under Common Control, and Joint Venture Formation [Abstract]
Adjustment Escrow
Adjustment Escrow [Member]
Adjustment Escrow
Stock issued, net proceeds
Sale of Stock, Consideration Received on Transaction
Total operating expenses
Costs and Expenses
Adoption Date
Trading Arrangement Adoption Date
Inventory
Inventory, Policy [Policy Text Block]
Counterparty Name [Domain]
Counterparty Name [Domain]
Total inventory
Inventory, Current And Noncurrent, Net
Inventory, Current And Noncurrent, Net
Total stockholders’ equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Total other income (expense), net
Nonoperating Income (Expense)
ASSETS
Assets:
Assets [Abstract]
Title
Trading Arrangement, Individual Title
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Total consideration for the transaction (in shares)
Business Combination, Consideration Transferred, Equity Interest, Share Issued, Number of Shares
Amortized Cost
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Accounting Policies [Abstract]
Restatement does not require Recovery
Restatement Does Not Require Recovery [Text Block]
Weighted-average risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Present value of operating lease payments
Total operating lease liability
Operating Lease, Liability
Issuance of common stock, net of issuance costs
Payments of Stock Issuance Costs
Insider Trading Policies and Procedures [Line Items]
Beginning balance (in shares)
Ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Insider Trading Policies and Procedures Adopted
Insider Trading Policies and Procedures Adopted [Flag]
Performance Stock Unit Activity
Performance Shares [Member]
Available-for-sale Debt Securities, Contractual Maturity Less Than 12 Months
Available-for-sale Debt Securities, Contractual Maturity Greater Than 12 Months [Member]
Available-for-sale Debt Securities, Contractual Maturity Greater Than 12 Months
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Selling, general and administrative
General and administrative
Selling, General and Administrative Expense
BALANCE SHEET ACCOUNT DETAIL
Supplemental Balance Sheet Disclosures [Text Block]
Business Combination [Domain]
Business Combination [Domain]
COMMITMENTS AND CONTINGENCIES
Commitments and Contingencies Disclosure [Text Block]
Compensation Actually Paid vs. Net Income
Compensation Actually Paid vs. Net Income [Text Block]
Outstanding and potentially dilutive securities excluded from computation of diluted net loss per share (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Number of operating segments
Number of Operating Segments
Restricted Stock Unit Activity
Restricted Stock Units (RSUs) [Member]
Schedule of Outstanding Potentially Dilutive Securities
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Entity Central Index Key
Entity Central Index Key
(Less): Accumulated depreciation
Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization
License fees and collaboration revenue
License fees and collaboration revenue
License And Collaboration [Member]
License And Collaboration
All Adjustments to Compensation
All Adjustments to Compensation [Member]
Business Combination [Axis]
Business Combination [Axis]
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member]
Income Taxes
Income Tax, Policy [Policy Text Block]
Net cash provided by (used in) operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Accounts Receivable
Accounts Receivable [Member]
Foreign
Foreign Income Tax Expense (Benefit), Continuing Operations
Income Statement [Abstract]
Stockholders’ equity:
Equity, Attributable to Parent [Abstract]
Shares issued in connection with the employee stock purchase plan (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Document Transition Report
Document Transition Report
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Gain on exchange of long-term investments
Gain on exchange of long-term investments
Gain (loss) on investments
Gain (Loss) on Investments
Operating expenses:
Operating expenses:
Operating Expenses [Abstract]
Schedule of Federal, State and Foreign Income Tax Provision (Benefit)
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Dr. Azamian and Dr. Link Private Company Transaction - Fair Value Of Preferred Units
Dr. Azamian And Dr. Link Private Company Transaction - Fair Value Of Preferred Units [Member]
Dr. Azamian And Dr. Link Private Company Transaction - Fair Value Of Preferred Units
Stock Appreciation Rights (SARs)
Stock Appreciation Rights (SARs) [Member]
Schedule of Valuation Assumptions of Stock Options
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Net proceeds
Proceeds from (Repayments of) Debt
Basis spread on variable rate (as a percent)
Debt Instrument, Basis Spread on Variable Rate
Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Accrued product sales deductions
Accrued Sales Commission, Current
City Area Code
City Area Code
Accumulated Other Comprehensive Income (Loss)
AOCI Attributable to Parent [Member]
Interest rate floor (as a percent)
Debt Instrument, Floor Interest Rate
Debt Instrument, Floor Interest Rate
All Individuals
All Individuals [Member]
Additions of intangible assets included within other accrued liabilities
Intangible Assets Expenditures Incurred But Not Yet Paid
Intangible Assets Expenditures Incurred But Not Yet Paid
Name
Forgone Recovery, Individual Name
Finished goods
Inventory, Finished Goods, Net of Reserves
Unrecognized compensation expense, weighted average period of recognition (in years)
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Contingent consideration, non-current
Business Combination, Contingent Consideration, Liability, Noncurrent
Non-GAAP Measure Description
Non-GAAP Measure Description [Text Block]
Weighted-Average Grant Date Fair Value ($)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Consideration on equity interest
Business Combination, Consideration Transferred, Equity Interest
Statement [Line Items]
Statement [Line Items]
Total assets
Assets
Accrued payroll and benefits
Business Combination, Recognized Liabilities Assumed, Accrued Payroll And Benefits
Business Combination, Recognized Liabilities Assumed, Accrued Payroll And Benefits
Entity [Domain]
Entity [Domain]
Amounts
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Commercial and Sales Milestones
Commercial And Sales Milestones [Member]
Commercial And Sales Milestones
Accounts Receivable, Net
Accounts Receivable [Policy Text Block]
Preferred stock, issued (in shares)
Preferred Stock, Shares Issued
Total shares of common stock reserved (in shares)
Common Stock, Capital Shares Reserved for Future Issuance
Stock-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Interest expense
Interest expense
Interest Expense, Nonoperating
Schedule of Stock-Based Compensation Expense
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Milestone Determined by the Company
Milestone Determined by the Company [Member]
Milestone Determined by the Company
Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Total liabilities assumed
Business Combination, Recognized Liability Assumed, Liability
STOCK-BASED COMPENSATION
Share-Based Payment Arrangement [Text Block]
Shares issued in connection with the employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock in private placement, net of issuance costs (in shares)
Stock Issued During Period, Shares, New Issues
Other accrued liabilities
Other accrued liabilities
Accounts Payable and Other Accrued Liabilities, Current
PEO
PEO [Member]
Prepaid expenses
Increase (Decrease) in Prepaid Expense
Total stock-based compensation
Share-Based Payment Arrangement, Expense
Marketable securities
Marketable Securities, Current
Other long-term liabilities
Other Liabilities, Noncurrent
Acquired clinical inventory
Business Combination, Recognized Asset Acquired, Inventory, Current
First Commercial Sale Milestone
First Commercial Sale Milestone [Member]
First Commercial Sale Milestone
Forgone Recovery due to Violation of Home Country Law, Amount
Forgone Recovery due to Violation of Home Country Law, Amount
Exercise of vested stock options (in shares)
Exercised (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Accounts payable
Business Combination, Recognized Liability Assumed, Accounts Payable, Current
Granted (usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Operating lease liability, non-current
Operating Lease, Liability, Noncurrent
Income tax payable, current
Taxes Payable, Current
Accumulated Deficit
Retained Earnings [Member]
Money market funds
Money Market Funds [Member]
Forfeited (usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Cash and cash equivalents
Business Combination, Recognized Asset Acquired, Cash and Cash Equivalent
Fair Value Measurements
Fair Value Measurement, Policy [Policy Text Block]
Erroneously Awarded Compensation Recovery
Erroneously Awarded Compensation Recovery [Table]
Forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Additional cash payment
Revenue, Remaining Performance Obligation, Additional Cash Payment
Revenue, Remaining Performance Obligation, Additional Cash Payment
Business Combination, Accounting Codification [Axis]
Business Combination, Accounting Codification [Axis]
Business Combination, Accounting Codification
Schedule of Quantitative Information About the Significant Unobservable Inputs
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common stock, outstanding (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Common Stock, Shares, Outstanding
Award Timing Disclosures [Line Items]
Schedule of Financial Instruments Measured at Fair Value
Fair Value, by Balance Sheet Grouping [Table Text Block]
Corporate debt securities
Corporate Debt Securities [Member]
Net loss per share - diluted (usd per share)
Earnings Per Share, Diluted
Clinical Milestones
Clinical Milestones [Member]
Clinical Milestones
Entity Current Reporting Status
Entity Current Reporting Status
License Agreement
Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member]
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Total Shareholder Return Amount
Total Shareholder Return Amount
Accrued payroll and benefits
Increase (Decrease) in Employee Related Liabilities
Reportable Segment
Reportable Segment [Member]
Reportable Segment
Weighted- Average Remaining Contractual Term (Years)
Share-based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term [Abstract]
Share-based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Amortization of intangible assets
Amortization expense
Intangible Asset, Finite-Lived, Amortization Expense
Schedule of Consideration Transferred
Business Combination [Table Text Block]
Research and development
Research and Development Expense
Research and Development Expense
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Dr. Azamian and Dr. Link Private Company Transaction - Preferred Stock Exchange Amount
Dr. Azamian And Dr. Link Private Company Transaction - Preferred Stock Exchange Amount [Member]
Dr. Azamian And Dr. Link Private Company Transaction - Preferred Stock Exchange Amount
Loss on initial consolidation of variable interest entity
Loss on initial consolidation of variable interest entity
Variable Interest Entity, Initial Consolidation, Gain (Loss)
Total assets acquired
Business Combination, Recognized Asset Acquired, Asset
Share-Based Payment Arrangement [Abstract]
Revenue recognized
Revenue from Contract with Customer, Excluding Assessed Tax
Cash Flows From Financing Activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Property and equipment, net
Property and equipment, net
Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization
Aggregate milestone payments upon achievement
Business Combination, Contingent Consideration, Milestone Payment, Amount
Business Combination, Contingent Consideration, Milestone Payment, Amount
Contractual maturity (in years)
Debt Securities, Available-for-Sale, Term
Financial Instruments [Domain]
Financial Instruments [Domain]
Contingent Consideration
Business Combination, Contingent Consideration [Policy Text Block]
Business Combination, Contingent Consideration
Accrued branded prescription drug fee
Accrued Branded Prescription Drug Fee, Current
Accrued Branded Prescription Drug Fee, Current
Intangible Asset, Finite-Lived, Class [Axis]
Intangible Asset, Finite-Lived, Class [Axis]
Exercise of vested stock options
Stock Issued During Period, Value, Stock Options Exercised
Business Combination, Milestone Payment, Type [Axis]
Business Combination, Milestone Payment, Type [Axis]
Business Combination, Milestone Payment, Type
Equity Awards Adjustments, Footnote
Equity Awards Adjustments, Footnote [Text Block]
Andrew Goldberg Plan January 4, 2027 [Member]
Andrew Goldberg Plan January 4, 2027
Underlying Securities
Award Underlying Securities Amount
Unvested (in years)
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Nonvested, Weighted Average Remaining Contractual Term
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Nonvested, Weighted Average Remaining Contractual Term
Andrew Goldberg Plan September 10, 2027 [Member]
Andrew Goldberg Plan September 10, 2027
Intangible assets, gross
Intangible Asset, Excluding Goodwill, before Accumulated Amortization
Issuance of common stock in private placement, net of issuance costs
Stock Issued During Period, Value, New Issues
Underwriters' option
Over-Allotment Option [Member]
Prepaid expenses
Prepaid Expense, Current
Forfeited (usd per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Inventory
Increase (Decrease) in Inventories
Common stock issued (in shares)
Stock Issued During Period, Shares, Acquisitions
Discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Segment Reporting [Table]
Segment Reporting [Table]
Issuance of pre-funded warrants in private placement, net of issuance costs
Adjustments To Additional Paid In Capital, Pre-Funded Warrants Issued, Issuance Costs
Adjustments To Additional Paid In Capital, Pre-Funded Warrants Issued, Issuance Costs
Schedule of Related Party Transactions, by Related Party [Table]
Related Party Transaction [Table]
Sale of Stock [Axis]
Sale of Stock [Axis]
Schedule of Components of Lease Cost
Lease, Cost [Table Text Block]
Marketable Securities and Long-Term Investments
Marketable Securities, Policy [Policy Text Block]
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies Disclosure [Abstract]
All Trading Arrangements
All Trading Arrangements [Member]
Beginning balance
Ending balance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Other Performance Measure, Amount
Other Performance Measure, Amount
Award Timing MNPI Considered
Award Timing MNPI Considered [Flag]
Office equipment
Office Equipment [Member]
Loss from operations before other income (expense)
Operating Income (Loss)
Current Fiscal Year End Date
Current Fiscal Year End Date
Valuation Allowance by Deferred Tax Asset [Axis]
Valuation Allowance by Deferred Tax Asset [Axis]
Non-PEO NEO Average Total Compensation Amount
Non-PEO NEO Average Total Compensation Amount
Maximum milestone payments
Collaborative Arrangement, Maximum Milestone Payment
Collaborative Arrangement, Maximum Milestone Payment
Related Party Transaction [Domain]
Related Party Transaction [Domain]
MERGERS AND ACQUISITIONS
Business Combination [Text Block]
Future cash payments
Collaborative Arrangement, Future Cash Payments
Collaborative Arrangement, Future Cash Payments
First Commercial Sales Milestone
First Commercial Sales Milestone [Member]
First Commercial Sales Milestone
Accrued royalty payable
Accrued Royalty Payable, Current
Accrued Royalty Payable, Current
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member]
Entity File Number
Entity File Number
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted [Flag]
Business Combination, Consideration Type [Domain]
Business Combination, Consideration Type [Domain]
Business Combination, Consideration Type [Domain]
Schedule of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Weighted- Average Exercise Price/Share ($)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Recovery of Erroneously Awarded Compensation Disclosure [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Common stock, issued (in shares)
Common Stock, Shares, Issued
Measure:
Measure [Axis]
One Customer
One Customer [Member]
One Customer
DESCRIPTION OF BUSINESS AND PRESENTATION OF FINANCIAL STATEMENTS
Business Description and Basis of Presentation [Text Block]
Acquisition-date fair value, expensed at closing
Business Combination, Recognized Asset Acquired, Identifiable Intangible Asset, Finite-Lived, Amount Expensed At Closing
Business Combination, Recognized Asset Acquired, Identifiable Intangible Asset, Finite-Lived, Amount Expensed At Closing
Long-Lived Assets Held-for-Sale by Asset Type [Axis]
Long-Lived Asset, Held-for-Sale, Type [Axis]
Contingent consideration
Business Combination, Contingent Consideration [Member]
Business Combination, Contingent Consideration
Equity Components [Axis]
Equity Components [Axis]
Accounts receivable, net
Increase (Decrease) in Accounts Receivable
Related Party
Related Party [Member]
Product and Service [Domain]
Product and Service [Domain]
Income taxes paid in cash
Income Tax Paid, after Refund Received
Common stock awards reserved for future issuance under the 2020 and 2016 Plans (in shares)
Common Stock, Capital Shares Reserved for Future Issuance, Effect Of Stock Awards Available For Future Grant
Common Stock, Capital Shares Reserved for Future Issuance, Effect Of Stock Awards Available For Future Grant
Entity Interactive Data Current
Entity Interactive Data Current
Payments for tenant improvement allowance
Payments for (Proceeds from) Tenant Allowance
Compensation Actually Paid vs. Other Measure
Compensation Actually Paid vs. Other Measure [Text Block]
Debt issuance costs
Debt Issuance Costs, Line of Credit Arrangements, Net
Entity Smaller Reporting Company
Entity Small Business
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
2029
Lessee, Operating Lease, Liability, to be Paid, Year Three
Termination Date
Trading Arrangement Termination Date
Upfront payment received
Collaborative Arrangement, Rights And Obligations, Upfront Payment
Collaborative Arrangement, Rights And Obligations, Upfront Payment
Property, Plant, and Equipment [Line Items]
Property, Plant, and Equipment [Line Items]
Assets acquired
Asset Acquisition, Assets Acquired,Net
Asset Acquisition, Assets Acquired,Net
LianBio
LianBio [Member]
LianBio
Acquisition-date fair value
Acquired IPR&D
Business Combination, Recognized Asset Acquired, Identifiable Intangible Asset, Finite-Lived
Compensation Actually Paid vs. Total Shareholder Return
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
MNPI Disclosure Timed for Compensation Value
MNPI Disclosure Timed for Compensation Value [Flag]
Other liabilities
Other Liabilities, Current
Contingent Consideration Related To Initial Consolidation Of Variable Interest Entity
Contingent Consideration Related To Initial Consolidation Of Variable Interest Entity [Member]
Contingent Consideration Related To Initial Consolidation Of Variable Interest Entity
Other assets
Other Assets, Noncurrent
Document Type
Document Type
Offering costs included within other accrued liabilities
Deferred Offering Costs Incurred But Not Yet Paid, Included In Other Accrued Liabilities
Deferred Offering Costs Incurred But Not Yet Paid, Included In Other Accrued Liabilities
Cash paid for the acquisition of Alkeus, net of cash acquired
Payments to Acquire Businesses, Net of Cash Acquired
Contractual milestone payment net sales
Collaborative Arrangement, Rights And Obligations, Contractual Milestone, Net Sales
Collaborative Arrangement, Rights And Obligations, Contractual Milestone, Net Sales
Fair Value as of Grant Date
Award Grant Date Fair Value
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES AND USE OF ESTIMATES
Significant Accounting Policies [Text Block]
Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Pay vs Performance Disclosure, Table
Pay vs Performance [Table Text Block]
Impairments of intangible assets
Intangible Asset, Excluding Goodwill, Impairment Loss
Arrangement Duration
Trading Arrangement Duration
Statement of Stockholders' Equity [Abstract]
Local Phone Number
Local Phone Number
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Entity Registrant Name
Entity Registrant Name
Schedule of Performance Stock Unit Activity
Share-Based Payment Arrangement, Performance Shares, Activity [Table Text Block]
Insider Trading Policies and Procedures Not Adopted
Insider Trading Policies and Procedures Not Adopted [Text Block]
Commitments and contingencies (Note 9)
Commitments and Contingencies
Total revenues
Total revenues
Revenues
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name [Domain]
Property and equipment, at cost
Property, Plant, and Equipment, before Accumulated Depreciation, Depletion, and Amortization
Changed Peer Group, Footnote
Changed Peer Group, Footnote [Text Block]
2030
Intangible Asset, Finite-Lived, Estimated Amortization Expense, Year Four
Manufacturing equipment
Machinery and Equipment [Member]
Forgone Recovery due to Expense of Enforcement, Amount
Forgone Recovery due to Expense of Enforcement, Amount
Executive Category:
Executive Category [Axis]
Counterparty Name [Axis]
Counterparty Name [Axis]
Furniture and fixtures
Furniture and Fixtures [Member]
Two Customers
Two Customers [Member]
Two Customers
LIABILITIES AND STOCKHOLDERS’ EQUITY
Liabilities and Equity [Abstract]
Intangible Asset, Finite-Lived, Class [Domain]
Intangible Asset, Finite-Lived, Class [Domain]
Exercisable (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term
Inventory
Inventory
Inventory, Net
Award Type [Domain]
Award Type [Domain]
Non-PEO NEO Average Compensation Actually Paid Amount
Non-PEO NEO Average Compensation Actually Paid Amount
2026 (remaining three months)
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
FAIR VALUE MEASUREMENTS
Fair Value Disclosures [Text Block]
Level 3
Fair Value, Inputs, Level 3 [Member]
Cash consideration paid to selling shareholders
Asset Acquisition, Consideration Transferred, Equity Interest Issued and Issuable
Unvested (usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
2027
Intangible Asset, Finite-Lived, Estimated Amortization Expense, Year One
Lease term (in years)
Lessee, Operating Lease, Term of Contract
Liabilities assumed
Asset Acquisition, Liabilities Assumed, Net
Asset Acquisition, Liabilities Assumed, Net
PEO Name
PEO Name
Potential additional tranches
Debt Instrument, Number Of Potential Additional Tranches
Debt Instrument, Number Of Potential Additional Tranches
Cambridge, Massachusetts
Cambridge, Massachusetts [Member]
Cambridge, Massachusetts
Geographical [Axis]
Geographical [Axis]
Leasehold improvements
Leasehold Improvements [Member]
Upfront payment
Contract with Customer, Liability
Other reconciling items
Segment Reporting, Other Segment Item, Amount
Long-Lived Asset, Class [Axis]
Long-Lived Asset, Class [Axis]
Concentration Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Stock Price or TSR Estimation Method
Stock Price or TSR Estimation Method [Text Block]
Entity Tax Identification Number
Entity Tax Identification Number
Liability, measurement input
Business Combination, Contingent Consideration, Liability, Measurement Input
Legal Entity [Axis]
Legal Entity [Axis]
Total interest expense
Interest Expense, Debt
2023 ATM Prospectus
2023 ATM Prospectus [Member]
2023 ATM Prospectus
Liability Class [Axis]
Liability Class [Axis]
Pharmakon Credit Facility, Tranche Three
Pharmakon Credit Facility, Tranche Three [Member]
Pharmakon Credit Facility, Tranche Three
Lessee, Lease, Description [Table]
Lessee, Lease, Description [Table]
Exercised (usd per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Revenue Recognition
Revenue [Policy Text Block]
Cash, cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Aggregate Erroneous Compensation Not Yet Determined
Aggregate Erroneous Compensation Not Yet Determined [Text Block]
Material Terms of Trading Arrangement
Material Terms of Trading Arrangement [Text Block]
Non-NEOs
Non-NEOs [Member]
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member]
Debt Instrument [Axis]
Debt Instrument [Axis]
Other long-term liabilities
Business Combination, Recognized Liability Assumed, Other Liability, Noncurrent
Cash consideration
Payments to Acquire Businesses, Gross
Asset Acquisitions and Acquired In-Process Research and Development (“IPR&D”)
Asset Acquisitions And In-Process Research and Development, Policy [Policy Text Block]
Asset Acquisitions And In-Process Research and Development, Policy
Stock-based compensation
Share-Based Payment Arrangement, Noncash Expense
2028
Intangible Asset, Finite-Lived, Estimated Amortization Expense, Year Two
Total lease expense
Lease, Cost
Fair market value of common stock (as a percent)
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Deferred Consideration [Axis]
Business Combination, Deferred Consideration, Type [Axis]
Business Combination, Deferred Consideration, Type
Schedule of Principal Balance of the 2024 Credit Facility
Schedule of Debt [Table Text Block]
Employee Stock Purchase Plan
Employee Stock [Member]
Related party transaction, amount of transaction
Related Party Transaction, Amounts of Transaction
Customer [Domain]
Customer [Domain]
Schedule of Inventories
Schedule of Inventory, Current [Table Text Block]
Long-term Debt, Type [Domain]
Long-Term Debt, Type [Domain]
Sales Royalty Earnout
Sales Royalty Earnout [Member]
Sales Royalty Earnout
Net loss per share - basic (usd per share)
Earnings Per Share, Basic
Measurement Input Type [Axis]
Measurement Input Type [Axis]
Total current assets
Assets, Current
Statistical Measurement [Axis]
Statistical Measurement [Axis]
Insider Trading Arrangements [Line Items]
Long-term debt, net
Long-Term Debt, Excluding Current Maturities
Award Type [Axis]
Award Type [Axis]
Named Executive Officers, Footnote
Named Executive Officers, Footnote [Text Block]
Accounts receivable, net
Accounts Receivable, after Allowance for Credit Loss, Current
Issuance of pre-funded warrants in private placement, net of issuance costs
Adjustments to Additional Paid in Capital, Warrant Issued
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Business Combination, Milestone Payment, Type [Domain]
Business Combination, Milestone Payment, Type [Domain]
Business Combination, Milestone Payment, Type [Domain]
Product and Service [Axis]
Product and Service [Axis]
Restricted cash, non-current
Restricted Cash, Noncurrent
Unvested (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Non-current assets:
Inventory, Noncurrent [Abstract]
Change in fair value of contingent consideration
Business Combination, Contingent Consideration, Change in Contingent Consideration, Liability, Increase (Decrease)
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member]
Upfront payment received
Upfront Payment
Upfront Payment
Commercial Sales Milestone Payments
Commercial Sales Milestone Payments [Member]
Commercial Sales Milestone Payments
Awards Close in Time to MNPI Disclosures
Awards Close in Time to MNPI Disclosures [Table]
Common Stock
Common Stock [Member]
Total marketable securities
Corporate debt securities
Debt Securities, Available-for-Sale
Contingent consideration
Contingent milestone consideration
Business Combination, Contingent Consideration, Liability
Operating lease expense
Operating Lease, Cost
Compensation Actually Paid vs. Company Selected Measure
Compensation Actually Paid vs. Company Selected Measure [Text Block]
Long-Lived Assets Held-for-Sale, Name [Domain]
Long-Lived Assets Held-for-Sale, Name [Domain]
Acquired inventory expensed
Acquired Inventory, Expensed
Acquired Inventory, Expensed
Cover [Abstract]
Aggregate Intrinsic Value
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Aggregate Intrinsic Value [Abstract]
Share-Based Compensation Arrangement By Share-Based Payment Award, Options, Aggregate Intrinsic Value
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Accrued clinical trials
Accrued Clinical Trials, Current
Accrued Clinical Trials, Current
Amounts
Intangible Asset, Finite-Lived, after Accumulated Amortization, Estimated Amortization Expense, Fiscal Year Maturity [Abstract]
Interest expense for long-term debt
Interest Expense, Debt, Excluding Amortization
Fair Value Measurement Inputs and Valuation Techniques [Table]
Fair Value Measurement Inputs and Valuation Techniques [Table]
Concentration risk (as a percent)
Concentration Risk, Percentage
Concentration Risk Benchmark [Axis]
Concentration Risk Benchmark [Axis]
Andrew Goldberg [Member]
Andrew Goldberg
Aggregate consideration, shares issued (in shares)
Asset Acquisition, Consideration Transferred, Equity Interest Issued, Shares
Asset Acquisition, Consideration Transferred, Equity Interest Issued, Shares
Equity Awards Adjustments
Equity Awards Adjustments [Member]
OUT-LICENSE AGREEMENT
Collaborative Arrangement Disclosure [Text Block]
Security deposit
Security Deposit Liability
Asset Acquisition [Line Items]
Asset Acquisition [Line Items]
Total liabilities and stockholders’ equity
Liabilities and Equity
Variable lease expense
Variable Lease, Cost
Interest income
Interest income
Interest Income, Other
Portion of cash and share consideration attributable to accelerated awards
Share-Based Payment Arrangement, Accelerated Cost
Stock Option Activity
Stock options, unexercised — vested and unvested
Share-Based Payment Arrangement, Option [Member]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Segments [Axis]
Segments [Axis]
Additional 402(v) Disclosure
Additional 402(v) Disclosure [Text Block]
Plan Name [Axis]
Plan Name [Axis]
Related Party [Domain]
Related and Nonrelated Parties [Domain]
Tabular List, Table
Tabular List [Table Text Block]
Additional paid-in capital
Additional Paid in Capital
Schedule of Estimated Value of Cash, Cash Equivalents, Marketable Securities, and Equity Securities
Unrealized Gain (Loss) on Investments [Table Text Block]
Other long-term liabilities
Increase (Decrease) in Other Noncurrent Liabilities
Other income (expense), net
Other Nonoperating Income (Expense)
Valuation Allowance [Line Items]
Valuation Allowance [Line Items]
Weighted-average volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Weighted Average Volatility Rate
Acquired in-process research and development
Acquired IPR&D expenses
Acquired In Process Research And Development Expense
Acquired In Process Research And Development Expense
2029
Intangible Asset, Finite-Lived, Estimated Amortization Expense, Year Three
Schedule of Other Accrued Liabilities
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
2026 (remaining three months)
Intangible Asset, Finite-Lived, Estimated Amortization Expense, Remainder of Fiscal Year
Name
Awards Close in Time to MNPI Disclosures, Individual Name
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member]
Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Forfeited (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Long-Lived Asset, Class [Domain]
Long-Lived Asset, Class [Domain]
Fair Value by Liability Class [Domain]
Fair Value by Liability Class [Domain]
Original issue price (usd per share)
Sale of Stock, Price Per Share
Business Combination, Contingent Consideration, Type [Domain]
Business Combination, Contingent Consideration, Type [Domain]
Preferred stock, authorized (in shares)
Preferred Stock, Shares Authorized
Other segment disclosures:
Segment Reporting, Other Disclosure [Abstract]
Property, Plant, and Equipment [Table]
Property, Plant, and Equipment [Table]
Follow-On Public Offering
Follow-On Public Offering [Member]
Follow-On Public Offering
Preferred stock, $0.0001 par value; 10,000,000 shares authorized; no shares issued and outstanding
Preferred Stock, Value, Issued
Equity interests issued attributable to accelerated options (in shares)
Business Combination, Equity Interests Issued, Attributable To Accelerated Options
Business Combination, Equity Interests Issued, Attributable To Accelerated Options
Adjustment to Compensation:
Adjustment to Compensation [Axis]
Cost of Sales
Cost of Goods and Service [Policy Text Block]
Accounts payable
Increase (Decrease) in Other Accounts Payable and Accrued Liabilities
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated [Flag]
Aggregate Erroneous Compensation Amount
Aggregate Erroneous Compensation Amount
Interest expense paid in cash
Interest Paid, Excluding Capitalized Interest, Operating Activity
Statement of Cash Flows [Abstract]
Selling, General and Administrative
Selling, General and Administrative Expenses, Policy [Policy Text Block]
In Process Research and Development
In Process Research and Development [Member]
Schedule of Total Shares Reserved For Future Issuance
Schedule of Stock by Class [Table Text Block]
Aggregate Available
Trading Arrangement, Securities Aggregate Available Amount
Total assets measured at fair value
Assets, Fair Value Disclosure
Name
Measure Name
INCOME TAXES
Income Tax Disclosure [Text Block]
Accounts payable
Accounts Payable, Current
Pay vs Performance Disclosure [Line Items]
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV [Domain]
Number of available-for-sale debt securities in gross unrealized loss position for less than one year
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Number of Positions
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Common stock awards reserved for future issuance under the 2020 ESPP (in shares)
Common Stock, Capital Shares Reserved for Future Issuance, Employee Stock Purchase Plan
Common Stock, Capital Shares Reserved for Future Issuance, Employee Stock Purchase Plan
Pay vs Performance Disclosure
Pay vs Performance Disclosure [Table]
Total consideration transferred
Total consideration transferred
Business Combination, Consideration Transferred
Additional Paid-In Capital
Additional Paid-in Capital [Member]
Entity Filer Category
Entity Filer Category
Cash paid for the acquisition of iRenix, net of cash acquired
Payments to Acquire Business Two, Net of Cash Acquired
Preferred stock investment exchanged for preferred units of privately-held company
Preferred Stock, Investment Exchanged For Preferred Units Of Privately Held Company
Preferred Stock, Investment Exchanged For Preferred Units Of Privately Held Company
Name
Trading Arrangement, Individual Name
Unrecognized compensation expense
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Amortized Cost
Cash and Cash Equivalent
Estimated period to payment
Measurement Input, Expected Term [Member]
Base rent expense
Operating Lease, Expense
Concentration Risk Benchmark [Domain]
Concentration Risk Benchmark [Domain]
Company Selected Measure Amount
Company Selected Measure Amount
Unrealized Gains
Cash And Cash Equivalents, Accumulated Unrealized Gains, Before Tax
Cash And Cash Equivalents, Accumulated Unrealized Gains, Before Tax
Schedule of Operating Financial Results of Therapeutics Segment
Segment Reporting, Reconciliation of Profit (Loss) by Segment to Consolidated [Table Text Block]
Depreciation and amortization expense
Depreciation, Depletion and Amortization
Deferred consideration included within accrued payroll and benefits
Deferred Offering Costs Incurred But Not Yet Paid, Included In Additional Paid In Capital
Deferred Offering Costs Incurred But Not Yet Paid, Included In Additional Paid In Capital
Federal
Federal Income Tax Expense (Benefit), Continuing Operations
Entity Address, Address Line Two
Entity Address, Address Line Two
Shares transferred (in usd per share)
Business Combination, Price Per Share
Current assets:
Current assets:
Assets, Current [Abstract]
Non-PEO NEO
Non-PEO NEO [Member]
Entity Address, Address Line One
Entity Address, Address Line One
Operating lease right-of-use asset obtained in exchange for operating lease liability
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Vested (usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Provision for income taxes
Provision for income taxes
Provision for income taxes
Income Tax Expense (Benefit)
Comprehensive Loss
Comprehensive Income, Policy [Policy Text Block]
Customer Concentration Risk
Customer Concentration Risk [Member]
Cost of sales
Cost of sales
Cost of Product and Service Sold
Award Timing Method
Award Timing Method [Text Block]
Common stock votes
Common Stock, Number Of Votes
Common Stock, Number Of Votes
Principles of Consolidation
Consolidation, Policy [Policy Text Block]
Net (decrease) increase in cash, cash equivalents and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Intangible Assets, Milestone Payment
Intangible Assets, Milestone Payment [Member]
Intangible Assets, Milestone Payment
Forgone Recovery, Explanation of Impracticability
Forgone Recovery, Explanation of Impracticability [Text Block]
Net loss
Net loss
Net loss
Net Income (Loss) Attributable to Parent
Long-term Debt, Type [Axis]
Long-Term Debt, Type [Axis]
Operating lease right-of-use assets
Business Combination, Recognized Identifiable Assets Acquired, Operating Lease, Right-of-Use Assets
Business Combination, Recognized Identifiable Assets Acquired, Operating Lease, Right-of-Use Assets
Erroneous Compensation Analysis
Erroneous Compensation Analysis [Text Block]
Share-Based Compensation
Share-Based Compensation [Member]
Share-Based Compensation
Statement [Table]
Statement [Table]
Proceeds from issuance of pre-funded warrants, net of paid issuance costs
Proceeds from Issuance of Warrants
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Restatement Determination Date:
Restatement Determination Date [Axis]
Proceeds from exercise of stock options
Proceeds from Stock Options Exercised
Milestone payments to be achieved
Revenue, Remaining Performance Obligation, Variable Consideration, Amount
Revenue, Remaining Performance Obligation, Variable Consideration, Amount
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Exercisable (usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Leases
Lessee, Leases [Policy Text Block]
Thereafter
Finite-Lived Intangible Asset, Expected Amortization, after Year Four
Finite-Lived Intangible Asset, Expected Amortization, after Year Four
Amount expensed at closing
Asset Acquisition, Consideration Transferred, Transaction Cost
Pharmakon Credit Facility, Tranche One
Pharmakon Credit Facility, Tranche One [Member]
Pharmakon Credit Facility, Tranche One
Unrealized (gain) loss from transactions denominated in a foreign currency
Unrealized Gain (Loss), Foreign Currency Transaction, before Tax
Restricted cash, non-current
Business Combination, Recognized Asset Acquired, Restricted Cash, Noncurrent
Business Combination, Recognized Asset Acquired, Restricted Cash, Noncurrent
Revenues:
Revenues:
Revenues [Abstract]
Pension Benefits Adjustments, Footnote
Pension Benefits Adjustments, Footnote [Text Block]
Prepaid expenses and other assets
Business Combination, Recognized Asset Acquired, Prepaid Expense and Other Asset, Current